Feed Additives 10% CAS 63283-36-3 Calcifediol Monohydrate / 25-Hydroxyvitamin D3 /(25-Hydroxyvitamin D3 / 25-Hydroxycholecalciferol

• Certification: QS, CCC, RoHS, ISO, CE
• Shape: Powder
• Type: Vitamin
• Color: White
• Function: Vitamin Additives
• Transport Package: 1kg Bag
• Model NO.: 25-Hydroxycholecalciferol
• Specification: 98%
• Trademark: VICTOR NUTRITION
• Origin: China
• HS Code: 2934999099
• Production Capacity: 5000000ton/Year

Product Description

Product Description

Calcifediol Monohydrate / 25-Hydroxyvitamin D3 / 25-Hydroxycholecalciferol CAS 63283-36-3

What is 25-hydroxyvitamin D3?

hydroxyvitamin D3(25-OH-D3), also know as 25-hydroxycholecalciferol, it is the metabolic product of the liver hydroxylation of vitamin D3. It is the main active form of vitamin D in human and animal blood circulation, and it is an indicator of the nutritional status of vitamin D3 in the body.

CAS-NO: 63283-36-3   

Formula: C27H44O2.H2O  

Molecular Weight: 418.7

Items

25-hydroxyvitamin D3

Regular vitamin D3

 

Absorption Pattern	Added a hydroxyl group, enhanced water solubility, independent of the micelle structure formed by bile secretion and fat absorption	The mode of absorption of fat-soluble vitamins depends on the micellar structure formed by bile secretion and fat absorption
Absorption Speed	Fast absorption - bypasses liver conversion and shortens the metabolic process of vitamin D3 in the body	A bit slow- has to be transformed by liver
Liver Influence	Unaffected by the liver dysfunction and reduce the burden of liver	Affected by liver's health
Bioactivity	Active metabolit, potency is 3-5 times final biological activity is 20-40 times	Inactive To be active need to convert into 25-hydroxyvitamin D3
Half life	20-22 days	25 days

25-hydroxyvitamin D3 Function(Pig for instance)

1.Strong Bones

2.Reproductivity

3.Mu scle Growth

4.Immunoregulation

Strong Bones Function

Helps on Bone

Promote the synthesis of calcium-binding protein by intestinal mucosal cells, increase the absorption of calcium and phosphorus by intestinal mucosal cells, increase blood calcium and phosphorus concentrations, and facilitate bone calcification.

Promote the re-absorption of calcium and phosphorus in the proximal convoluted tubule of the kidney, reduce the excretion of urinary calcium and phosphorus, increase the blood calcium level, and increase the bone density.

Directly acts on the mineral metabolism of bone, promotes the formation of bone matrix and osteoid mineralization, promotes the differentiation of mesenchymal cells into osteoclasts, dissolves bone salts, increases the concentration of blood calcium and phosphorus, which is beneficial to the calcification of new bones and promotes osteogenesis effect.

Regardless of whether the blood calcium level is normal or not, 25OHD3 and parathyroid hormone can interact, convert and excrete, so 5-10 times the dosage of 25OHD3 in pigs will not have adverse effects.

Helps On Reproduction

1.Improve the screening rate of gilts and prolong the service life of sows

2.Reduce manual intervention in the delivery process and reduce the occurrence of delivery complications

3.Improve the quality and quantity of boar semen, improve the conception rate and yield of sows

4.Increase piglet weaning litter weight

Helps On Mu scle Growth

By increasing the number of fetal myofibroblasts, suckling pigs can obtain more muscle fibers after birth, which is beneficial to later mu scle growth

Increases growth factors and genes that contribute to muscle production, promotes more differentiation of stem cells into myoblasts, and improves myotube formation.

Stimulate the muscle calcium level, increases the protease activity in muscle, and improves the water holding capacity of meat, thereby promoting the tenderization of meat and the improvement of meat color.

Helps On Immunity

Enhances the ability of monocytes to transform into macrophages and the phagocytic ability of macrophages such as the expression of beta defensin-beta2 in intestinal epithelial cells

Improve the number and vitality of immune cells, significantly increase the level of rotavirus antibodies in the serum and intestinal tract of weaned piglets, and effectively block the intestinal endotoxin (LPS) and the invasion of Escherichia coli to the intestinal tract.